Normal CD4 Count Range among Healthy Nigerian Population in Ilorin | Zendy

JosephK Afolabi | Zendy; Abayomi Fadeyi | Zendy; Olufemi Olumuyiwa Desalu | Zendy; I. A. Durotoye | Zendy; AE Fawibe | Zendy; Man Adeboye | Zendy; H.O. Olawumi | Zendy; Abiola Babatunde | Zendy; Samuel Kolade Ernest | Zendy; S.A. Aderibigbe | Zendy; R. Saadu | Zendy; Aisha Salami | Zendy; AP Aboyeji | Zendy

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Normal CD4 Count Range among Healthy Nigerian Population in Ilorin

Author(s) -

JosephK Afolabi,

Abayomi Fadeyi,

Olufemi Olumuyiwa Desalu,

I. A. Durotoye,

AE Fawibe,

Man Adeboye,

H.O. Olawumi,

Abiola Babatunde,

Samuel Kolade Ernest,

S.A. Aderibigbe,

R. Saadu,

Aisha Salami,

AP Aboyeji

Publication year - 2014

Publication title -

journal of the international association of providers of aids care (jiapac)

Language(s) - English

Resource type - Journals

eISSN - 2325-9582

pISSN - 2325-9574

DOI - 10.1177/2325957414530472

Subject(s) - nigerians , reference range , complete blood count , medicine , count data , absolute neutrophil count , reference values , blood count , population , statistics , mathematics , neutropenia , environmental health , toxicity , political science , law , poisson distribution

Background: For the establishment and monitoring of the immune status, CD4 count is critical.Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value.Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables.Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm 3 (19%-48%) and for children was 582 to 3652 cells/mm 3 (17%-50%). CD4 count and percentage of CD4 were significantly ( P = .001) higher in females than in males, and the CD4 count declined significantly with increasing age ( r = −.174, P ≤ .0001). The percentage of CD4 count shows less variation with age ( r = −.051, P = .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 ± 260) than that of the national reference values of 847.0 ± 307.0 cells/mm 3 ( P = .001).Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values.

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