Factors Associated with Late Initiation of Highly Active Antiretroviral Therapy among Young HIV-Positive Men and Women Aged 18 to 29 Years in Canada
Author(s) -
Alexis Palmer,
Angela Cescon,
Keith Chan,
Curtis Cooper,
Janet Raboud,
Caroline Miller,
Ann N. Burchell,
Marina B. Klein,
Nimâ Machouf,
Julio Montaner,
Chris Tsoukas,
Robert S. Hogg,
Mona Loutfy
Publication year - 2013
Publication title -
journal of the international association of providers of aids care (jiapac)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.813
H-Index - 31
eISSN - 2325-9582
pISSN - 2325-9574
DOI - 10.1177/2325957413510606
Subject(s) - interquartile range , medicine , antiretroviral therapy , logistic regression , cohort , cohort study , human immunodeficiency virus (hiv) , young adult , demography , observational study , viral load , pediatrics , immunology , sociology
Initiating highly active antiretroviral therapy (HAART) with low CD4 counts or AIDS-defining illnesses (ADIs) increases risk of treatment failure and death. We examined factors associated with late initiation among 18- to 29-year-olds within the Canadian Observational Cohort (CANOC) collaboration, a multi-site study of HIV-positive persons who initiated HAART after 2000. Late initiation was defined as beginning HAART with a CD4 count 25 years at initiation, initiating treatment in earlier years, and having higher baseline viral load. The high number of young adults in our cohort starting HAART late indicates important target populations for specialized services, increased testing, and linkages to care.
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