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Acute Pancreatitis in a Patient With COVID-19 After the Resolution of Respiratory Symptoms
Author(s) -
Hafiz Muhammad Jeelani,
Muhammad Mubbashir Sheikh,
Shirly Samuel,
Yetunde B Omotosho,
Artem Sharko,
Rami Albetar
Publication year - 2021
Publication title -
journal of investigative medicine high impact case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 10
ISSN - 2324-7096
DOI - 10.1177/23247096211024773
Subject(s) - medicine , pancreatitis , tmprss2 , covid-19 , respiratory system , acute pancreatitis , epigastric pain , gastroenterology , pathogenesis , intensive care medicine , disease , infectious disease (medical specialty) , vomiting
The gastrointestinal (GI) involvement, including acute pancreatitis (AP) from the novel coronavirus disease-2019 (COVID-19), is increasingly being reported. Recent evidence suggests that the pathogenesis of COVID-19 is mediated by the angiotensin-converting enzyme 2 (ACE-2) receptors and transmembrane protease serine 2 (TMPRSS2) for “priming,” which is highly expressed in the pancreas. To our knowledge, there is no other reported case of AP associated with COVID-19 after the respiratory symptoms are resolved. In this article, we present a patient with COVID-19, who came with intractable epigastric pain and resolved respiratory symptoms. A diagnosis of AP complicated with COVID-19 was made after laboratory and imaging workup, which was successfully managed conservatively.

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