The probiotic Bifidobacterium in the management of Coronavirus: A theoretical basis
Author(s) -
Hüseyin Sancar Bozkurt,
Eamonn M.M. Quigley
Publication year - 2020
Publication title -
international journal of immunopathology and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.724
H-Index - 53
eISSN - 2058-7384
pISSN - 0394-6320
DOI - 10.1177/2058738420961304
Subject(s) - immune system , cytokine storm , probiotic , immunology , cytokine , bifidobacterium , coronavirus , gastrointestinal tract , bacteria , microbiology and biotechnology , respiratory tract , lactobacillus casei , medicine , biology , lactobacillus , covid-19 , disease , respiratory system , infectious disease (medical specialty) , genetics
COVID-19 is a viral pandemic that primarily manifests with respiratory distress but may also lead to symptoms and signs associated with the gastrointestinal tract. It is characteristically associated with a hyper-immune response, also referred to as a ‘cytokine storm’. Probiotics are living microorganisms that have been shown to have positive effects on immune response in man with some bacteria; some strains of Bifidobacteria, for example, possess especially potent immune modulating effects. These bacteria have the potential to ameliorate the ‘cytokine storm’ through a differential effect on pro- and anti-inflammatory cytokines. In the management of COVID-19 and other coronovirus-mediated illnesses, probiotic bacteria also have the potential to enhance vaccine efficacy.
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