Open AccessPredictors and characteristics of angioectasias in patients with obscure gastrointestinal bleeding identified by video capsule endoscopy
Author(s) -
Nennstiel Simon,
Machanek Annkathrin,
Delius Stefan,
Neu Bruno,
Haller Bernhard,
Abdelhafez Mohamed,
Schmid Roland M,
Schlag Christoph
Publication year - 2017
Publication title -
ueg journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.667
H-Index - 35
eISSN - 2050-6414
pISSN - 2050-6406
DOI - 10.1177/2050640617704366
Subject(s) - medicine , capsule endoscopy , odds ratio , obscure gastrointestinal bleeding , gastrointestinal bleeding , confidence interval , gastroenterology , univariate analysis , multivariate analysis
Background In obscure gastrointestinal bleeding, angioectasias are common findings in video capsule endoscopy (VCE). Objective The objective of this study was to identify predictors and characteristics of small bowel angioectasias. Methods Video capsule examinations between 1 July 2001 and 31 July 2011 were retrospectively reviewed. Patients with obscure gastrointestinal bleeding were identified, and those with small bowel angioectasia were compared with patients without a definite bleeding source. Univariate and multivariable statistical analyses for possible predictors of small bowel angioectasia were performed. Results From a total of 717 video capsule examinations, 512 patients with obscure gastrointestinal bleeding were identified. Positive findings were reported in 350 patients (68.4%) and angioectasias were documented in 153 of these patients (43.7%). These angioectasias were mostly located in the proximal small intestine ( n = 86, 56.6%). Patients’ age >65 years (odds ratio (OR) 2.15, 95% confidence interval (CI) 1.36–3.38, p = .001) and overt bleeding type (OR 1.89, 95% CI 1.22–2.94, p = .004) were identified as significant independent predictors of small bowel angioectasia. Conclusion Angioectasias are the most common finding in VCE in patients with obscure gastrointestinal bleeding. They are mostly located in the proximal small bowel and are associated with higher age and an overt bleeding type.