Open AccessEndoscopic ultrasound in gastric cancer staging before and after neoadjuvant chemotherapy. A comparison with PET‐CT in a clinical series
Author(s) -
RedondoCerezo Eduardo,
MartínezCara Juan Gabriel,
JiménezRosales Rita,
ValverdeLópez Francisco,
CaballeroMateos Antonio,
JérvezPuente Pablo,
ArizaFernández Jose Luis,
ÚbedaMuñoz Margarita,
LópezdeHierro Mercedes,
Teresa Javier
Publication year - 2017
Publication title -
ueg journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.667
H-Index - 35
eISSN - 2050-6414
pISSN - 2050-6406
DOI - 10.1177/2050640616684697
Subject(s) - medicine , endoscopic ultrasound , radiology , cancer , cancer staging , pet ct , diagnostic accuracy , nuclear medicine , positron emission tomography
Background Treatment of gastric cancer is based on accurate staging. Emerging methods, such as PET‐CT, are increasingly being used for this purpose. Our aim was to analyze the results of EUS and PET‐CT in staging and restaging our patients with gastric cancer, comparing both of them with the histological results. Methods Patients with confirmed gastric cancer were prospectively enrolled. Inclusion criteria for the final analysis included only patients who finally received a surgical resection. All patients underwent preoperative TNM staging by means of EUS and PET‐CT within 21 days prior to the surgical treatment. Results A total of 256 patients were included. The overall EUS accuracy for T staging was 78% and 80.2% in restaging. EUS showed its best accuracy when distinguishing T1–T2 tumors vs. T3–T4, with an increased accuracy in restaging. Regarding N staging, the overall accuracy of EUS was 76.2%, and 72.5% for PET‐CT ( p = 0.02). With regards to restaging, accuracy of EUS and PET‐CT for N staging was 88.5% and 69%, respectively, with significant differences ( p < 0.0001). Conclusions EUS performed better than PET‐CT in gastric cancer N staging and restaging. EUS accuracy in this setting is still suboptimal and probably more than one single diagnostic procedure should be used.