Open AccessCombined effect of posttraumatic stress disorder and prescription opioid use on risk of cardiovascular disease
Author(s) -
Jeffrey F. Scherrer,
Joanne Salas,
Patrick J. Lustman,
Peter W. Tuerk,
Sarah Gebauer,
Sonya B. Norman,
Frank Schneider,
Kathleen M. Chard,
Carissa van den BerkClark,
Beth E. Cohen,
Paula P. Schnurr
Publication year - 2019
Publication title -
european journal of preventive cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.669
H-Index - 101
eISSN - 2047-4881
pISSN - 2047-4873
DOI - 10.1177/2047487319850717
Subject(s) - medicine , hazard ratio , confidence interval , proportional hazards model
Prescription opioid analgesic use (OAU) is associated with increased risk of cardiovascular disease (CVD). OAU is more common in patients with than without posttraumatic stress disorder (PTSD), and PTSD is associated with higher CVD risk. We determined whether PTSD and OAU have an additive or multiplicative association with incident CVD.