Open AccessRetrospective study of clinical characteristics and viral etiologies of patients with viral pneumonia in Beijing
Author(s) -
Zhao Xiang,
Meng Yao,
Li Duo,
Feng Zhaomin,
Huang Weijuan,
Li Xiyan,
Wei Hejiang,
Zeng Xiaoxu,
Wang Dayan
Publication year - 2021
Publication title -
pulmonary circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 40
ISSN - 2045-8940
DOI - 10.1177/20458940211011027
Subject(s) - medicine , viral pneumonia , pneumonia , human metapneumovirus , rhinovirus , mycoplasma pneumoniae , virus , virology , viral load , immunology , bronchoalveolar lavage , respiratory tract infections , respiratory system , lung , disease , covid-19 , infectious disease (medical specialty)
Aims The virus is common in patients with viral pneumonia. However, the viral etiology and clinical features of patients with viral pneumonia in China remain unclear. The main purpose of this study was to analyze the viral causes and epidemiology of patients with viral pneumonia in Beijing, which can significantly improve the pertinence and accuracy of clinical treatment of the disease. Methods Firstly, 1539 respiratory specimens of pneumonia (oropharyngeal swabs, nasopharyngeal swabs, saliva samples and bronchoalveolar lavage fluid) were collected from 19 hospitals in Beijing from September 2015 to August 2018. Then, TaqMan low‐density microfluidic chip technology was used to detect viral pneumonia specimens in 1539 respiratory tract specimens of pneumonia and determine the types of viral bacteria in them. Lastly, the analysis of demographic, clinical and etiological data of patients with viral pneumonia was performed. Results The results showed that among the 1539 respiratory tract specimens with pneumonia, 760 were detected as viral pneumonia specimens, with a positive rate of 49.4%. Among which, 467 were infected with mono‐viral and 293 were infected with multi‐viral. Influenza A virus (Flu A), mycoplasma pneumoniae (MPn), Ebola virus (EBV) and herpes simplex virus type 1 (HSV‐1) were the major viral components in the samples of these patients. Furthermore, these viral species were significantly associated with sample sources, onset season and certain clinical characteristics. Discussion Our findings may provide corresponding treatment strategies for viral pneumonia patients infected with specific viruses.