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Non-Alcoholic Fatty Liver Disease
Author(s) -
HuiHui Tan,
Jason PikEu Chang
Publication year - 2010
Publication title -
proceedings of singapore healthcare
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
eISSN - 2059-2329
pISSN - 2010-1058
DOI - 10.1177/201010581001900106
Subject(s) - steatohepatitis , fatty liver , cirrhosis , steatosis , medicine , liver biopsy , gastroenterology , metabolic syndrome , alcoholic liver disease , gold standard (test) , disease , biopsy , obesity
Non-alcoholic fatty liver disease (NAFLD) comprises a disease spectrum ranging from benign hepatic steatosis to non-alcoholic steatohepatitis with inflammation (NASH) and liver cirrhosis. NAFLD is now recognised as the hepatic manifestation of the metabolic syndrome. Simple steatosis is benign, whereas NASH can progress to cirrhosis with its resultant complications. Liver biopsy remains the gold standard in the diagnosis of NAFLD/NASH. Lifestyle and dietary modifications to achieve sustained weight loss is the cornerstone of NAFLD/NASH treatment.

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