Open AccessBicelle Composed of 1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine and Sodium Cholate
Author(s) -
Noriyuki Uchida,
Masayoshi Yanagi,
Hiroki Hamada
Publication year - 2022
Publication title -
natural product communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.221
H-Index - 44
eISSN - 1934-578X
pISSN - 1555-9475
DOI - 10.1177/1934578x221092702
Subject(s) - chemistry , model lipid bilayer , phospholipid , phosphatidylcholine , nuclear magnetic resonance , sodium cholate , molecule , nuclear magnetic resonance spectroscopy , analytical chemistry (journal) , crystallography , membrane , lipid bilayer , chromatography , stereochemistry , organic chemistry , lipid bilayer phase behavior , biochemistry , physics
A mixture of 1,2-dipalmitoyl- sn-glycero-3-phosphatidylcholine (DPPC) phospholipid and sodium chelate (SC) formed bicelles (DPPC–SC bicelle) at around 50 °C. In 2 H nuclear magnetic resonance (NMR) measurement of the dispersion of DPPC–SC bicelle, quadrupole splitting of D 2 O, an index of the ability to orient molecules, was observed.