Open AccessSecondary Metabolites of the Endophytic Fungus Chaetomium globosum Isolated From Coptis chinensis
Author(s) -
Jia-Cheng Ji,
Panpan Wei,
Xiaoyang Han,
Zhenghui Li,
HongLian Ai,
Xinxiang Lei
Publication year - 2021
Publication title -
natural product communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.221
H-Index - 44
eISSN - 1934-578X
pISSN - 1555-9475
DOI - 10.1177/1934578x211044574
Subject(s) - chaetomium globosum , coptis chinensis , chaetomium , chemistry , mass spectrometry , absolute configuration , plant use of endophytic fungi in defense , electrospray ionization , fungus , botany , stereochemistry , biology , chromatography , fusarium , medicine , alternative medicine , pathology , traditional chinese medicine
A new steroid, chaetglotone (1), together with 3 known compounds (2-4), were isolated from Chaetomium globosum, which is an endophytic fungus isolated from the root of Coptis chinensis Franch . The new compound was characterized by one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy and high-resolution electrospray ionization mass spectrometer. The relative configuration and absolute configuration of 1 were further determined via the DP4 + and Early Childhood Development protocols, separately.