Open AccessCorrelation between hemolytic profile and phylotype of Cutibacterium acnes (formerly Propionibacterium acnes) and orthopedic implant infection
Author(s) -
Julia Lee,
Kerryl E. Greenwood Quaintance,
Audrey N. Schuetz,
Dave R. Shukla,
Robert H. Cofield,
John W. Sperling,
Robin Patel,
Joaquín Sánchez-Sotelo
Publication year - 2019
Publication title -
shoulder and elbow
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.506
H-Index - 15
eISSN - 1758-5740
pISSN - 1758-5732
DOI - 10.1177/1758573219865884
Subject(s) - medicine , propionibacterium acnes , acne , phylotype , orthopedic surgery , hemolysis , dermatology , surgery , biology , bacteria , 16s ribosomal rna , genetics
Cutibacterium acnes is a recognized culprit for implant-associated infections, but positive cultures do not always indicate clinically relevant infection. Studies have shown a correlation between the β-hemolytic phenotype of C. acnes and its infectious capacity, but correlation with genetic phylotype has not been performed in literature. The purpose of this study is to evaluate β-hemolysis phenotype, genetic phylotype, and mid-term clinical outcomes of C. acnes isolated from orthopedic surgical sites.