Oxygen therapy via high flow nasal cannula in severe respiratory failure caused by Sars-Cov-2 infection: a real-life observational study | Zendy

Giada Procopio | Zendy; Anna Cancelliere | Zendy; Enrico Maria Trecarichi | Zendy; Maria Mazzitelli | Zendy; Eugenio Arrighi | Zendy; Graziella Perri | Zendy; Francesca Serapide | Zendy; Corrado Pelaia | Zendy; Elena Lio | Zendy; Maria Teresa Busceti | Zendy; Maria Chiara Pelle | Zendy; Marco Ricchio | Zendy; Vincenzo Scaglione | Zendy; Chiara Davoli | Zendy; Paolo Fusco | Zendy; Valentina La Gamba | Zendy; Carlo Torti | Zendy; Girolamo Pelaia | Zendy

Open Access

Oxygen therapy via high flow nasal cannula in severe respiratory failure caused by Sars-Cov-2 infection: a real-life observational study

Author(s) -

Giada Procopio,

Anna Cancelliere,

Enrico Maria Trecarichi,

Maria Mazzitelli,

Eugenio Arrighi,

Graziella Perri,

Francesca Serapide,

Corrado Pelaia,

Elena Lio,

Maria Teresa Busceti,

Maria Chiara Pelle,

Marco Ricchio,

Vincenzo Scaglione,

Chiara Davoli,

Paolo Fusco,

Valentina La Gamba,

Carlo Torti,

Girolamo Pelaia

Publication year - 2020

Publication title -

therapeutic advances in respiratory disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.022

H-Index - 37

eISSN - 1753-4666

pISSN - 1753-4658

DOI - 10.1177/1753466620963016

Subject(s) - nasal cannula , medicine , continuous positive airway pressure , ards , oxygen therapy , respiratory failure , intensive care medicine , pneumonia , anesthesia , respiratory distress , mechanical ventilation , positive airway pressure , cannula , covid-19 , disease , lung , surgery , infectious disease (medical specialty) , obstructive sleep apnea

The worldwide spread of coronavirus disease 2019 (COVID-19), caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared a pandemic by the World Health Organization (WHO) in March 2020. According to clinical studies carried out in China and Italy, most patients experience mild or moderate symptoms; about a fifth of subjects develop a severe and critical disease, and may suffer from interstitial pneumonia, possibly associated with acute respiratory distress syndrome (ARDS) and death. In patients who develop respiratory failure, timely conventional oxygen therapy through nasal catheter plays a crucial role, but it can be used only in mild forms. Continuous positive airway pressure (CPAP) support or non-invasive mechanical ventilation (NIV) are uncomfortable, and require significant man–machine cooperation. Herein we describe our experience of five patients with COVID-19, who were treated with high-flow nasal cannula (HFNC) after failure of CPAP or NIV, and discuss the role of HFNC in COVID-19 patients. Our findings suggest that HFNC can be used successfully in selected patients with COVID-19-related ARDS. The reviews of this paper are available via the supplemental material section.

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