Open AccessComposite grading algorithm for the National Cancer Institute’s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)
Author(s) -
Ethan Basch,
Conny Becker,
Lauren J. Rogak,
Deborah Schrag,
Bryce B. Reeve,
Patricia A. Spears,
Mary Lou Smith,
Mrinal M. Gounder,
Michelle R. Mahoney,
Gary K. Schwartz,
Antonia V. Bennett,
Tito R. Mendoza,
Charles S. Cleeland,
Jeff A. Sloan,
Deborah Watkins Bruner,
Gisela Schwab,
Thomas M. Atkinson,
Gita Thanarajasingam,
Monica M. Bertagnolli,
Amylou C. Dueck
Publication year - 2020
Publication title -
clinical trials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.559
H-Index - 63
eISSN - 1740-7753
pISSN - 1740-7745
DOI - 10.1177/1740774520975120
Subject(s) - common terminology criteria for adverse events , adverse effect , terminology , medicine , grading (engineering) , algorithm , clinical trial , data mining , computer science , philosophy , linguistics , civil engineering , engineering
The Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events is an item library designed for eliciting patient-reported adverse events in oncology. For each adverse event, up to three individual items are scored for frequency, severity, and interference with daily activities. To align the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events with other standardized tools for adverse event assessment including the Common Terminology Criteria for Adverse Events, an algorithm for mapping individual items for any given adverse event to a single composite numerical grade was developed and tested.