Open AccessRisk Factors for Gestational Diabetes Mellitus: A Case-Control Study
Author(s) -
Fatemeh Nasiri Amiri,
Mahbobeh Faramarzi,
Afsaneh Bakhtiari,
Shabnam Omidvar
Publication year - 2018
Publication title -
american journal of lifestyle medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 37
eISSN - 1559-8284
pISSN - 1559-8276
DOI - 10.1177/1559827618791980
Subject(s) - medicine , gestational diabetes , odds ratio , body mass index , confidence interval , obstetrics , diabetes mellitus , obesity , pregnancy , prenatal care , case control study , gestation , endocrinology , population , environmental health , biology , genetics
Background : The underlying causes of gestational diabetes mellitus (GDM) are important because they are effective for the diagnosis and prevention of this condition. The aim of this study was to identify the risk factors for GDM and the possible etiological agents. Materials and Methods : This case-control study was conducted with 100 women with GDM and 100 healthy pregnant women at a tertiary care hospital, affiliated to Babol University. GDM was identified by impaired oral glucose tolerance test based on the Carpenter and Coustan criteria. Healthy women were randomly selected from the prenatal health care clinic of the same center and were matched to gestational age of 24 to 28 weeks. Descriptive and inferential statistics were used for data analysis via the SPSS software. Results : After adjusting variables, multivariate analysis identified 4 significant risk factors of GDM, including prepregnancy low physical activity (odds ratio [OR] = 2.85, 95% confidence interval [CI]= 0.97-8.34), advanced maternal age (OR = 1.24, 95% CI = 1.13-1.35), body mass index ⩾ 30 kg/m 2 (OR = 1.10, 95% CI = 1.02-1.20), and family history of diabetes mellitus (OR = 5.62, 95% CI = 2.26-13.96). Conclusion : We observed significant associations between low prepregnancy physical activity and obesity with GDM risk. Thus the finding of this study can help devise strategies for the prevention of GDM.