z-logo
open-access-imgOpen Access
Mother-to-Child HIV Transmission in a Cohort of Pregnant Women Diagnosed by Rapid HIV Testing at Tijuana General Hospital, Baja California, Mexico
Author(s) -
Rolando M. Viani,
Jorge Ruiz-Calderon,
Graciano Lopez,
Enrique Chacón-Cruz,
Stephen A. Spector
Publication year - 2010
Publication title -
journal of the international association of physicians in aids care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.813
H-Index - 31
eISSN - 1557-0886
pISSN - 1545-1097
DOI - 10.1177/1545109710363920
Subject(s) - medicine , zidovudine , prenatal care , obstetrics , pregnancy , confidence interval , transmission (telecommunications) , human immunodeficiency virus (hiv) , cohort , cohort study , pediatrics , population , viral disease , family medicine , environmental health , biology , electrical engineering , genetics , engineering
This study evaluated an obstetrical program using rapid HIV testing for the prevention of mother-to-child HIV transmission (MTCT) in Baja California, Mexico. Between 2003 and 2005, 45 women in labor and 17 prenatal care women were HIV infected. Among labor patients, 14 (31%) delivered by cesarean section compared with 17 (100%) prenatal care patients (P < .001). Intravenous maternal zidovudine (ZDV) and infant oral ZDV were more frequently administered in prenatal care compared to labor patients: 94% versus 33% (P < .001) and 100% versus 79% (P < .001), respectively. All prenatal care women received combination therapy. All 10 HIV-infected infants were in the labor group, resulting in a MTCT rate of 23% (95% confidence interval [CI] 9.5-34.8) compared to 0% (95% CI 0-1.8; P < .001) among the prenatal care group. Five (50%) of the HIV-infected infants had an AIDS diagnosis and 2 (20%) died within 18 months of birth. Women diagnosed during labor had a high HIV MTCT and poor postnatal outcome.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here