Ang (1–7) is a modulator of the vasoconstrictor actions of Ang I and Ang II | Zendy

Jazmín FloresMonroy | Zendy; Ignacio ValenciaHernández | Zendy; Luisa Martínez-Aguilar | Zendy

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Ang (1–7) is a modulator of the vasoconstrictor actions of Ang I and Ang II

Author(s) -

Jazmín FloresMonroy,

Ignacio ValenciaHernández,

Luisa Martínez-Aguilar

Publication year - 2015

Publication title -

journal of the renin-angiotensin-aldosterone system

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 46

eISSN - 1752-8976

pISSN - 1470-3203

DOI - 10.1177/1470320314563560

Subject(s) - losartan , captopril , angiotensin ii receptor type 1 , angiotensin ii , contraction (grammar) , medicine , renin–angiotensin system , endocrinology , antagonist , chemistry , pharmacology , receptor , blood pressure

The role of angiotensin (Ang) (1-7) on the vasoconstrictor effect induced by angiotensins could be different in the presence of an ACE inhibitor or an ARB because Ang II is formed through several pathways. Therefore, the role of Ang (1-7) in Ang I and Ang II contraction was evaluated in aortas from Wistar rats after 48-hour coronary occlusion treated with captopril or losartan.

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