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Bone marrow angiotensin AT2receptor deficiency aggravates atherosclerosis development by eliminating macrophage liver X receptor-mediated anti-atherogenic actions
Author(s) -
Taku Kato,
Hiroyuki Kawahito,
Sou Kishida,
Daisuke Irie,
Noriyuki Wakana,
Masakazu Kikai,
Hiroki Takata,
Takehiro Ogata,
Tomomi Ueyama,
Satoaki Matoba,
Hiroyuki Yamada
Publication year - 2014
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320314561138
Subject(s) - angiotensin ii , apolipoprotein e , endocrinology , medicine , proinflammatory cytokine , liver x receptor , cholesterol , angiotensin ii receptor type 1 , abca1 , bone marrow , abcg1 , inflammation , receptor , biology , biochemistry , transporter , disease , nuclear receptor , transcription factor , gene
Bone marrow (BM) Angiotensin II (Ang II) type 1 (AT1) receptor plays a crucial role in atherosclerosis development; however, the effect of BM Ang II type 2 (AT2) receptor on atherogenesis remains undefined.

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