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A polymorphism (-455G>A) in the β-fibrinogen gene is associated with an increased risk of cerebral infarction in the Chinese population: A meta-analysis
Author(s) -
SaiYu Cheng,
Yandong Zhao,
Junwei Zeng,
Xiaohong Chen,
Ruo-Dan Wang
Publication year - 2014
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320314549222
Subject(s) - meta analysis , odds ratio , confidence interval , publication bias , fibrinogen , cerebral infarction , funnel plot , medicine , population , bioinformatics , genetics , biology , ischemia , environmental health
Previous studies have investigated the association between a polymorphism (-455 G>A) in the β-fibrinogen gene and the risk of cerebral infarction. However, these results are controversial. To shed light on these inconclusive findings, we performed a meta-analysis of studies relating the β-fibrinogen genetic polymorphism (-455 G>A) to the risk of cerebral infarction.

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