Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism and angiotensin-converting enzyme inhibition on erythropoiesis in patients on haemodialysis | Zendy

Zoltán Kiss | Zendy; Csaba Ambrus | Zendy; Imre Kulcsár | Zendy; János Szegedi | Zendy; István Kiss | Zendy; Attila Benke | Zendy; B. Borbás | Zendy; Sándor Ferenczi | Zendy; Mária Hengsperger | Zendy; Szilvia Kazup | Zendy; Lajos Nagy | Zendy; József Németh | Zendy; Antal Rozinka | Zendy; Tamás Szabó | Zendy; T Szelestei | Zendy; Eszter N. Tóth | Zendy; Gábor Varga | Zendy; Gyula Wágner | Zendy; Gábor Zakar | Zendy

Open Access

Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism and angiotensin-converting enzyme inhibition on erythropoiesis in patients on haemodialysis

Author(s) -

Zoltán Kiss,

Csaba Ambrus,

Imre Kulcsár,

János Szegedi,

István Kiss,

Attila Benke,

B. Borbás,

Sándor Ferenczi,

Mária Hengsperger,

Szilvia Kazup,

Lajos Nagy,

József Németh,

Antal Rozinka,

Tamás Szabó,

T Szelestei,

Eszter N. Tóth,

Gábor Varga,

Gyula Wágner,

Gábor Zakar

Publication year - 2014

Publication title -

journal of the renin-angiotensin-aldosterone system

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.457

H-Index - 46

eISSN - 1752-8976

pISSN - 1470-3203

DOI - 10.1177/1470320314535276

Subject(s) - erythropoiesis , medicine , angiotensin converting enzyme , genotype , erythropoietin , endocrinology , gene polymorphism , gastroenterology , polymorphism (computer science) , allele , anemia , biology , gene , genetics , blood pressure

Angiotensin-converting enzyme inhibitors (ACEis) improve survival; however, their effect on erythropoiesis remains a matter of debate in this population. Since insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene largely influences serum ACE activity, its effect on erythropoiesis is also anticipated.

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