A core promoter variant of angiotensinogen gene and interindividual variation in response to angiotensin-converting enzyme inhibitors
Author(s) -
Huimin Yu,
Lin Shu-guang,
Jiuchang Zhong,
Min He,
Lijun Jin,
Yuqing Zhang,
Guozhang Liu
Publication year - 2014
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320313506481
Subject(s) - angiotensin converting enzyme , gene , renin–angiotensin system , enzyme , angiotensin ii , core (optical fiber) , medicine , biology , endocrinology , genetics , biochemistry , receptor , materials science , blood pressure , composite material
The polymorphic angiotensinogen (AGT) gene is one of the most promising candidates for essential hypertension. The aim of this study was to examine the association between the A-6G variant of the AGT gene and the blood pressure response to angiotensin-converting enzyme (ACE) inhibitors in hypertensive subjects.
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