
A core promoter variant of angiotensinogen gene and interindividual variation in response to angiotensin-converting enzyme inhibitors
Author(s) -
Yu Hou,
Shu Lin,
Jiuchang Zhong,
Mingwei He,
Lina Jin,
Yuqing Zhang,
Guozhang Liu
Publication year - 2014
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320313506481
Subject(s) - blood pressure , genotype , genotyping , angiotensin converting enzyme , medicine , pulse pressure , renin–angiotensin system , angiotensin ii , endocrinology , gene , biology , polymerase chain reaction , genetics
The polymorphic angiotensinogen (AGT) gene is one of the most promising candidates for essential hypertension. The aim of this study was to examine the association between the A-6G variant of the AGT gene and the blood pressure response to angiotensin-converting enzyme (ACE) inhibitors in hypertensive subjects.