Open AccessAssociation between polymorphisms of the renin–angiotensin system and coronary artery disease in Chinese patients with type 2 diabetes
Author(s) -
He-Ping Lei,
Hongmei Chen,
Qingzhou Yao,
Honghong Tan,
Min Yang,
Qian Lin,
ZhiXin Shan,
Zhiwei Zheng,
Ji-Xiao Zhu,
ZhiLing Zhou,
Shu Lin,
Xiang Yu
Publication year - 2012
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320311435533
Subject(s) - multifactor dimensionality reduction , medicine , genotyping , coronary artery disease , type 2 diabetes , genotype , diabetes mellitus , angiotensin converting enzyme , polymorphism (computer science) , allele , gene polymorphism , renin–angiotensin system , logistic regression , bioinformatics , endocrinology , gene , genetics , biology , single nucleotide polymorphism , blood pressure
The renin-angiotensin system (RAS) is regarded as one of the most important regulatory systems for cardiovascular homeostasis. In this study, we investigated associations of the five genetic polymorphisms in the RAS and presence of coronary artery disease (CAD) in type 2 diabetes.