Effects of antihypertensive treatment on endothelial function in postmenopausal hypertensive women. A significant role for aldosterone inhibition
Author(s) -
Rosario Rossi,
Annachiara Nuzzo,
Daniele Iaccarino,
A Lattanzi,
Giorgia Origliani,
Daniel Monopoli,
Maria Grazia Modena
Publication year - 2011
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320311415134
Subject(s) - medicine , brachial artery , blood pressure , endothelial dysfunction , cardiology , population , confidence interval , odds ratio , aldosterone , environmental health
Endothelial dysfunction is a well-demonstrated independent predictor of cardiovascular events in hypertensive postmenopausal women. Accordingly, it is plausible that improving endothelial function could represent an adjunctive target for antihypertensive treatment. The aim of our study was to evaluate the effect of pharmacologic treatment on endothelial function in the specific population of hypertensive postmenopausal women.
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