Open AccessSympathetic and angiotensinergic responses mediated by paradoxical sleep loss in rats
Author(s) -
Juliana C. Perry,
Cássia T. Bergamaschi,
Rui Campos,
Mônica Levy Andersen,
Nicola Montano,
Dulce Elena Casarini,
Sérgio Tufik
Publication year - 2011
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320310391504
Subject(s) - sleep deprivation , medicine , blood pressure , endocrinology , heart rate , sleep (system call) , renin–angiotensin system , splanchnic , hemodynamics , circadian rhythm , computer science , operating system
Recent investigations over the past decade have linked the development of hypertension to sleep loss, although the mechanisms underlying this association are still under scrutiny. To determine the relationship between sleep deprivation and cardiovascular dysfunction, we examined the effects of paradoxical sleep deprivation on heart rate, blood pressure, sympathetic nerve activity (SNA) and their consequences in the blood renin-angiotensin system.