Open AccessEarly expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism
Author(s) -
Miguel Copaja Soto,
Yesenia Valenzuela,
Y. Adiela Saldana,
María Paz Ocaranza,
Jorge Jalil,
Carlos P. Vio,
Paul Lijnen,
Gamaliel E. Ordenes,
Raúl Vivar Sánchez,
Sergio Lavandero,
Guillermo Dı́az-Araya
Publication year - 2008
Publication title -
jraas. journal of the renin-angiotensin-aldosterone system/journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.1177/1470320308096408
Subject(s) - medicine , endocrinology , angiotensin ii , fibrosis , fibronectin , monocyte , ventricle , cardiac fibrosis , angiotensin converting enzyme , chemistry , cell , biochemistry , blood pressure
Isoproterenol treatment of Brown Norway and Lewis rats (high and low plasma angiotensin-I-converting enzyme activity, respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in Brown Norway rats.