Sensitivity of T1/T2-weighted ratio in detection of cortical demyelination is similar to magnetization transfer ratio using post-mortem MRI | Zendy

Yufan Zheng | Zendy; Jessica Dudman | Zendy; Jacqueline T. Chen | Zendy; Kedar Mahajan | Zendy; Danielle Herman | Zendy; Robert J. Fox | Zendy; Daniel Ontaneda | Zendy; Bruce D. Trapp | Zendy; Kunio Nakamura | Zendy

Open Access

Sensitivity of T1/T2-weighted ratio in detection of cortical demyelination is similar to magnetization transfer ratio using post-mortem MRI

Author(s) -

Yufan Zheng,

Jessica Dudman,

Jacqueline T. Chen,

Kedar Mahajan,

Danielle Herman,

Robert J. Fox,

Daniel Ontaneda,

Bruce D. Trapp,

Kunio Nakamura

Publication year - 2021

Publication title -

multiple sclerosis journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.729

H-Index - 131

eISSN - 1477-0970

pISSN - 1352-4585

DOI - 10.1177/13524585211014760

Subject(s) - multiple sclerosis , magnetic resonance imaging , magnetization transfer , medicine , nuclear medicine , white matter , myelin , pathology , radiology , central nervous system , psychiatry

Detecting cortical demyelination using magnetic resonance imaging (MRI) in multiple sclerosis (MS) remains a challenge. Magnetization transfer ratio (MTR), T1-weighted/T2-weighted ratio (T1T2R), and T2-weighted (T2w) signal are sensitive to cortical demyelination, but their accuracy is unknown.

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