Open AccessSerum ceramide levels are altered in multiple sclerosis
Author(s) -
Angeliki Filippatou,
Mohammed Moniruzzaman,
Elias S. Sotirchos,
Kathryn C. Fitzgerald,
Grigorios Kalaitzidis,
Jeffrey Lambe,
Eleni Vasileiou,
Shiv Saidha,
Jerry L. Prince,
Norman J. Haughey,
Peter A. Calabresi,
Pavan Bhargava
Publication year - 2020
Publication title -
multiple sclerosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.729
H-Index - 131
eISSN - 1477-0970
pISSN - 1352-4585
DOI - 10.1177/1352458520971816
Subject(s) - expanded disability status scale , odds ratio , sphingolipid , multiple sclerosis , medicine , confidence interval , ceramide , nerve fiber layer , endocrinology , atrophy , retinal , ophthalmology , biology , immunology , biochemistry , apoptosis
Sphingolipids are myelin components and inflammatory signaling intermediates. Sphingolipid metabolism may be altered in people with multiple sclerosis (PwMS), but existing studies are limited by small sample sizes.