Open AccessRadiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes
Author(s) -
Paul Ramia,
Larry Bodgi,
Dima Mahmoud,
Mohammad Ali Mohammad,
Bassem Youssef,
Neil Kopek,
Humaid O. AlShamsi,
Mona Dagher,
Ibrahim AbuGheida
Publication year - 2022
Publication title -
clinical medicine insights. oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 26
ISSN - 1179-5549
DOI - 10.1177/11795549211036898
Subject(s) - medicine , head and neck cancer , etiology , radiation therapy , head and neck , presentation (obstetrics) , intensive care medicine , pathogenesis , cancer , bioinformatics , oncology , surgery , biology
Radiotherapy-related fibrosis remains one of the most challenging treatment related side effects encountered by patients with head and neck cancer. Several established and ongoing novel therapies have been studied with paucity of data in how to best treat these patients. This review aims to provide researchers and health care providers with a comprehensive review on the presentation, etiology, and therapeutic options for this serious condition.