Open AccessBenign mixed Müllerian (duct) vaginal tumor in a 12-y-old goat
Author(s) -
Svenja Hartung,
Elfi K. Schlohsarczyk,
Alexandra Jost,
Marlene Sickinger,
Kernt Köhler
Publication year - 2022
Publication title -
journal of veterinary diagnostic investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.529
H-Index - 78
eISSN - 1943-4936
pISSN - 1040-6387
DOI - 10.1177/10406387211069370
Subject(s) - malignancy , vagina , differential diagnosis , smooth muscle , medicine , pathology , müllerian mimicry , female circumcision , leiomyoma , gross examination , duct (anatomy) , smooth muscle tumor , genital tract , gynecology , anatomy , physiology
In human and veterinary medicine, mixed Müllerian tumors (MMTs) are rarely diagnosed neoplasms of the tubular female genital tract. Although there are case reports of malignant MMTs in various species, benign MMTs have only been described once in a macaque. Here we present a case of benign MMT in a 12-y-old goat, and review the literature on uterine, cervical, and vaginal neoplasia in goats. The doe was presented with vaginal discharge and was euthanized because of the high suspicion of intraabdominal neoplasia. On gross examination, an ulcerated vaginal mass was identified. Histologically, 2 distinct cell populations were present: smooth muscle cells that were well differentiated and positive for alpha–smooth muscle actin, and ciliated columnar epithelial cells that lined ductal structures and had no signs of malignancy. These findings led to the diagnosis of neoplasia of Müllerian origin. Benign MMT should be considered as a differential diagnosis for uterine and vaginal neoplasms in goats.