Open AccessPleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis
Author(s) -
Vivian Kawai,
Mingjian Shi,
Ge Liu,
Feng Qi,
Wei Qi Wei,
Cecilia P. Chung,
Theresa L. Walunas,
Adam S. Gordon,
James G. Linneman,
Scott J. Hebbring,
John B. Harley,
Nancy J. Cox,
Dan M. Roden,
C. Michael Stein,
Jonathan D. Mosley
Publication year - 2021
Publication title -
lupus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.069
H-Index - 103
eISSN - 1477-0962
pISSN - 0961-2033
DOI - 10.1177/09612033211014952
Subject(s) - medicine , phenome , single nucleotide polymorphism , pleiotropy , genome wide association study , type 2 diabetes , genetic epidemiology , allele , diabetes mellitus , disease , phenotype , genetics , genotype , endocrinology , biology , gene
To test the hypothesis that genetic predisposition to systemic lupus erythematosus (SLE) increases the risk of cardiometabolic disorders.