Open AccessPostseptic Cognitive Impairment and Expression of APOE in Peripheral Blood: The Cognition After SepsiS (CASS) Observational Pilot Study
Author(s) -
Samuel M. Brown,
Sarah J. Beesley,
Chris Stubben,
Emily L. Wilson,
Angela P. Presson,
Colin K. Grissom,
Colin T. Maguire,
Matthew T. Rondina,
Ramona O. Hopkins
Publication year - 2020
Publication title -
journal of intensive care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 58
eISSN - 1525-1489
pISSN - 0885-0666
DOI - 10.1177/0885066619897604
Subject(s) - medicine , prospective cohort study , executive dysfunction , cognition , cohort , observational study , sepsis , cohort study , apolipoprotein e , oncology , neuropsychology , psychiatry , disease
Cognitive impairment after sepsis is an important clinical problem. Determinants of postseptic cognitive impairment are not well understood. We thus undertook a systems biology approach to exploring a possible role for apolipoprotein E (APOE) in postseptic cognitive impairment.