Clinical Research: Is Routine Vitamin K Supplementation Required in Hospitalized Patients Receiving Parenteral Nutrition? | Zendy

Duerksen Donald R. | Zendy; Papineau Noreen | Zendy

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Clinical Research: Is Routine Vitamin K Supplementation Required in Hospitalized Patients Receiving Parenteral Nutrition?

Author(s) -

Duerksen Donald R.,

Papineau Noreen

Publication year - 2000

Publication title -

nutrition in clinical practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.725

H-Index - 71

eISSN - 1941-2452

pISSN - 0884-5336

DOI - 10.1177/088453360001500205

Subject(s) - medicine , parenteral nutrition , multivitamin , incidence (geometry) , vitamin , vitamin k deficiency , vitamin k , gastroenterology , physics , optics

Vitamin K is not a component of the multivitamin preparation added to parenteral nutrition solutions, and hospitalized patients receiving parenteral nutrition (PN) support are at risk of developing vitamin K deficiency. In this study, 70 consecutive patients receiving PN were followed prospectively to determine the incidence of a raised international normalized ratio (INR). Over a 3‐week period, 20% of patients developed a raised INR compared with baseline. All elevations were mild, with no patients developing clinical bleeding. An alternative to routinely supplementing vitamin K is monitoring INR and supplementing those individuals with elevated coagulation parameters.

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