Open AccessVitrified Particulated Articular Cartilage for Joint Resurfacing: A Swine Model
Author(s) -
Kezhou Wu,
Kar Wey Yong,
Maha Ead,
Mark Sommerfeldt,
Tamara D. Skene-Arnold,
Lindsey Westover,
Kajsa Duke,
Leila Laouar,
Janet A.W. Elliott,
Nadr M. Jomha
Publication year - 2022
Publication title -
the american journal of sports medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.021
H-Index - 221
eISSN - 1552-3365
pISSN - 0363-5465
DOI - 10.1177/03635465221123045
Subject(s) - cartilage , osteoarthritis , cryopreservation , chondrocyte , histology , articular cartilage , staining , andrology , anatomy , medicine , chemistry , surgery , pathology , biology , embryo , microbiology and biotechnology , alternative medicine
The use of particulated articular cartilage for repairing cartilage defects has been well established, but its use is currently limited by the availability and short shelf life of donor cartilage. Vitrification is an ice-free cryopreservation technology at ultralow temperatures for tissue banking. An optimized vitrification protocol has been developed for particulated articular cartilage; however, the equivalency of the long-term clinical efficacy of vitrified particulated articular cartilage compared with fresh articular cartilage has not yet been determined.