Open AccessA novel, injury-free rodent model of vulnerability for assessment of acute and preventive therapies reveals temporal contributions of CGRP-receptor activation in migraine-like pain
Author(s) -
Caroline Machado Kopruszinski,
Edita Navratilova,
Juliana Swiokla,
David W. Dodick,
Iain P. Chessell,
Frank Porreca
Publication year - 2020
Publication title -
cephalalgia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.57
H-Index - 125
eISSN - 1468-2982
pISSN - 0333-1024
DOI - 10.1177/0333102420959794
Subject(s) - medicine , allodynia , sumatriptan , migraine , hyperalgesia , anesthesia , calcitonin gene related peptide , pharmacology , receptor antagonist , agonist , antagonist , receptor , nociception , neuropeptide
Development and characterization of a novel injury-free preclinical model of migraine-like pain allowing mechanistic assessment of both acute and preventive treatments.