Open AccessCorrelation between nerve atrophy, brain grey matter volume and pain severity in patients with primary trigeminal neuralgia
Author(s) -
Yuan Wang,
Qian Yang,
Dong-Yuan Cao,
David A. Seminowicz,
Bethany Remeniuk,
Lin Gao,
Ming Zhang
Publication year - 2018
Publication title -
cephalalgia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.57
H-Index - 125
eISSN - 1468-2982
pISSN - 0333-1024
DOI - 10.1177/0333102418793643
Subject(s) - medicine , trigeminal neuralgia , grey matter , trigeminal nerve , voxel based morphometry , anesthesia , magnetic resonance imaging , radiology , white matter
Recent neuroimaging studies have reported grey matter alterations in primary trigeminal neuralgia patients. However, few studies have focused on quantitative measurements of trigeminal nerves and the interaction between trigeminal nerve volume and brain morphology, particularly grey matter volume. In this study, we investigated the link between trigeminal nerves and grey matter volume changes in primary trigeminal neuralgia patients compared to healthy controls. Moreover, we explored the association of structure of trigeminal nerves and grey matter to collected pain clinical variables.