Open AccessIncreasing age associated with elevated cardio–ankle vascular index scores in patients with type 2 diabetes mellitus
Author(s) -
Tian Gao,
Wen-mei Wei,
Wei Zhang,
Ling Zhang,
Hongshuai You,
Lei Wen,
Zhu Sun,
Xiaobing Wang,
Xiao Wu
Publication year - 2013
Publication title -
journal of international medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 57
eISSN - 1473-2300
pISSN - 0300-0605
DOI - 10.1177/0300060513477290
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , arterial stiffness , type 2 diabetes mellitus , risk factor , cardiology , bayesian multivariate linear regression , blood pressure , linear regression , endocrinology , machine learning , computer science
Objective The study investigated the relationship between arterial stiffness calculated using the cardio–ankle vascular index (CAVI), diagnosis of type 2 diabetes mellitus and type 2 diabetes-related cardiovascular complications, in patients with type 2 diabetes mellitus (type 2 diabetes) and nondiabetic patients.Methods A retrospective cross-sectional study was conducted in patients with type 2 diabetes and age-matched nondiabetic patients. CAVI was measured using an automatic vascular screening system. Parameters associated with type 2 diabetes and cardiovascular complications were also measured.Results A total of 51 patients with type 2 diabetes and 59 nondiabetic patients were enrolled in the study. Significantly higher CAVI scores were observed in patients with type 2 diabetes compared with nondiabetic patients (mean ± SD: 9.55 ± 1.13 versus 8.54 ± 0.94, respectively). Multivariate linear regression analyses demonstrated that age was the only significant factor influencing the CAVI score, in patients with type 2 diabetes.Conclusion Patients with type 2 diabetes had an increased risk of arterial stiffness, based on the CAVI score, compared with nondiabetic patients; this, in turn, could increase their risk of developing other cardiovascular complications.