Recipient IL-6-572C/G genotype is associated with reduced incidence of acute rejection following liver transplantation
Author(s) -
Jia Yao,
Xiaowen Feng,
Xiaobo Yu,
Haiyang Xie,
Zhu Lixian,
Zhe Yang,
Bajin Wei,
Shusen Zheng,
Lin Zhou
Publication year - 2013
Publication title -
journal of international medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 57
eISSN - 1473-2300
pISSN - 0300-0605
DOI - 10.1177/0300060513477264
Subject(s) - medicine , genotype , liver transplantation , single nucleotide polymorphism , incidence (geometry) , gastroenterology , snp , allele , transplantation , gene , genetics , biology , physics , optics
Acute rejection resulting from alloimmune responses is a major risk factor affecting patient survival following liver transplantation. Since interleukin (IL)-6 can mediate acute rejection, the association between IL-6 gene single nucleotide polymorphisms (SNPs) and incidence of acute rejection in liver transplant recipients was investigated.
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