Open AccessAcute micro-thrombosis after subarachnoid hemorrhage: A new therapeutic target?
Author(s) -
Fenghui Ye,
Richard F. Keep,
Ya Hua,
Hugh Garton,
Guohua Xi
Publication year - 2021
Publication title -
journal of cerebral blood flow and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.167
H-Index - 193
eISSN - 1559-7016
pISSN - 0271-678X
DOI - 10.1177/0271678x211013595
Subject(s) - subarachnoid hemorrhage , medicine , thrombolysis , thrombosis , ischemia , intracranial thrombosis , cardiology , venous thrombosis , myocardial infarction
Microthrombi formation in the brain following subarachnoid hemorrhage (SAH) has been recognized and suspected to contribute to cerebral ischemia. A recent study found that ultra-early cerebral micro-thrombosis occured four hours after experimental SAH. The number of thrombotic microvessels correlated with brain-blood barrier disruption and neuronal injury. If acute cerebral micro-thrombi also occur in humans, is it time to develop a therapy with systemic thrombolysis for SAH patients?
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