Open AccessThe effect of relative cerebral hyperperfusion during cardiac surgery with cardiopulmonary bypass to delayed neurocognitive recovery
Author(s) -
Greta Kasputytė,
Rasa Bukauskienė,
Edmundas Širvinskas,
Ilona Razlevičė,
Tomas Bukauskas,
Tadas Lenkutis
Publication year - 2022
Publication title -
perfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.653
H-Index - 45
eISSN - 1477-111X
pISSN - 0267-6591
DOI - 10.1177/02676591221129737
Subject(s) - medicine , cardiopulmonary bypass , anesthesia , cerebral blood flow , neurocognitive , cardiac surgery , middle cerebral artery , cerebral autoregulation , transcranial doppler , postoperative cognitive dysfunction , cardiology , surgery , ischemia , autoregulation , blood pressure , cognition , psychiatry
Delayed neurocognitive recovery (dNCR) remains a common complication after surgery and the incidence of it is determined 30-80% after cardiac surgery with cardiac bypass (CPB) in eldery patients. Many researchers have identified that neuropsychological complications emerge from insufficient cerebral perfusion. Relative cerebral hyperperfusion also disrupts cerebral autoregulation and might play a significant role in dNCR development. The aim of this study is to determine hyperperfusion in the middle cerebral artery during CPB influence to dNCR development and brain biomarker glial fibrillary acidic protein (GFAP) impact in diagnosing dNCR.