Open AccessExperiences of Sublingual Immunotherapy in Allergic Rhinitis
Author(s) -
Lee HeungMan,
Choi Hyuk,
Park IlHo,
Kim YongDae
Publication year - 2011
Publication title -
otolaryngology–head and neck surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.232
H-Index - 121
eISSN - 1097-6817
pISSN - 0194-5998
DOI - 10.1177/0194599811415823a405
Subject(s) - sublingual immunotherapy , medicine , slit , dust mites , adverse effect , quality of life (healthcare) , nose , allergy , dermatology , surgery , immunology , allergen , nursing , biology , genetics
Objective Sublingual immunotherapy (SLIT) is currently used worldwide as an allergic rhinitis management tool. The purpose of this study was to investigate the efficacy and safety of SLIT for Asian patients with allergic rhinitis to house dust mites. Method Ninety‐eight patients who had allergic rhinitis for dermatophagoides were included and started to receive SLIT. Symptom scores and quality of life were evaluated before and until 1 year by questionnaires. Medication score was assessed monthly by a diary medication card. Adverse effects and compliance were also investigated. Results All nasal and non‐nasal symptoms and quality of life were significantly improved after treatment except itchy palate ( P <. 05). Total medication score was decreased after treatment significantly ( P <. 05). Some minor adverse effects was reported, however there was no systemic reaction. The drop‐out rate was 19%. Conclusion SLIT for Korean patients with allergic rhinitis to house dust mites is an efficient and safe treatment tool.