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Prevention of Catheter‐Related Sepsis During Parenteral Nutrition: Effect of a NeW Connection Device
Author(s) -
Inoue Yoshifumi,
Nezu Rchiro,
Matsuda Hikaru,
Fuj Makoto,
Nakai Sumio,
Wasa Masafumi,
Takagi Yoji,
Okada Akira
Publication year - 1992
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607192016006581
Subject(s) - medicine , parenteral nutrition , catheter , sepsis , surgery , anesthesia
A prospective study was carried out to determine the clinical effect of a newly devised catheter connection method (I system) and piggyback access system. Previous studies have demonstrated that the I system avoided bacterial contamination in vitro during tubing change that Luer‐Lock connectors did not. The purpose of this study was to investigate the ability of this device coupled with a new closed‐system piggyback technique for multipurpose access to reduce catheter‐related sepsis in clinical practice. Two hundred and thirty patients receiving total parenteral nutrition were divided into two groups. Group I (n = 106) used the I system connector and group L (n = 124) used a Luer‐Lock connector. Catheters in both groups were used for multipurpose access for infusion and blood sampling. In group L, a three‐way stopcock and/or piggyback system was used for multiple access. In group I, a newly designed closed‐system piggyback was used. The incidence of catheter‐related sepsis was significantly lower in group I (1.89%/catheter) than in group L (12.10%/catheter) (p <.01, χ 2 analysis), and the average duration of use of each catheter was significantly longer in group I than in Group L (p <.01 by generalized Wilcoxon test). The results of this clinical study suggest that the newly designed connection method and piggyback access system are able to reduce catheter‐related sepsis. (Journal of Parenteral and Enteral Nutrition 16 :581–585, 1992)