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Hormonal and Metabolic Response to Operative Stress in the Neonate
Author(s) -
Schmeling David J.,
Coran Arnold G.
Publication year - 1991
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607191015002215
Subject(s) - anabolism , hormone , catabolism , enteral administration , medicine , endocrine system , glucagon , parenteral nutrition , endocrinology , insulin , fight or flight response , insulin resistance , biology , metabolism , biochemistry , gene
It is evident from this review that newborns, even those born prematurely, are capable of mounting an endocrine and metabolic response to operative stress. Unfortunately, many of the areas for which a relatively well‐characterized response exists in adults are poorly documented in neonates. As is the case in adults, the response seems to be primarily catabolic in nature because the combined hormonal changes include an increased release of catabolic hormones such as catecholamines, glucagon, and corticosteroids coupled with a suppression of and peripheral resistance to the effects of the primary anabolic hormone, insulin. (Journal of Parenteral and Enteral Nutrition 15: 215–238, 1991)