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Pulmonary Deposition of Calcium Phosphate Crystals as a Complication of Home Total Parenteral Nutrition
Author(s) -
Knowles Jarol B.,
Cusson Gil,
Smith Marilyn,
Sitrin Michael D.
Publication year - 1989
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607189013002209
Subject(s) - parenteral nutrition , calcium , enteral administration , phosphate , complication , medicine , phosphorus , crystallization , gastroenterology , chemistry , biochemistry , organic chemistry
A patient on home total parenteral nutrition (TPN) developed a diffuse granulomatous interstitial pneumonitis secondary to calcium phosphate deposition. Calcium and phosphorus concentrations in the TPN formula were not unusually high, indicating that other factors contributed to calcium phosphate crystallization. The effects of duration of storage of the TPN formulation, solution temperature, pH, and magnesium concentration on calcium phosphate precipitation are discussed. ( Journal of Parenteral and Enteral Nutrition 13 :209–213, 1989)