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Splanchnic glucose balance and insulin resistance in the early postoperative phase of cardiac surgery
Author(s) -
Nilsson F,
Ekroth R,
Milocco I,
Nilsson NJ,
Svensson S,
Berglin E,
WilliamOlsson G
Publication year - 1988
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607188012006574
Subject(s) - splanchnic , hyperinsulinemia , basal (medicine) , medicine , liter , insulin , abdominal surgery , endocrinology , balance (ability) , insulin resistance , postprandial , blood flow , physical medicine and rehabilitation
The splanchnic balance of glucose was studied in the basal state and at three levels of “clamped” hyperinsulinemia (260 +/‐ 23, 510 +/‐ 59, 3875 +/‐ 367 mU/liter) in 24 patients (43–70 years of age), who had undergone coronary surgery about 1 hr previously. The splanchnic balance of glucose in the basal state was negative in all patients (‐1.6 +/‐ 0.3 mg/kg/min) and was changed into a zero‐balance within 30 min when 0.15 or 0.3 U/kg/hr of insulin was infused. At an insulin infusion rate of 1.0 U/kg/hr the net splanchnic glucose balance was turned into a significant positive balance of an average 0.9 +/‐ 0.3 mg/kg/min.