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A New Apparatus for Chronic Intravenous Infusion in Unrestrained Rats
Author(s) -
Takeyama Hiromitsu,
Yura Jiro,
Miyaike Hideo,
Ishikawa Masakazu,
Mizuno Hiroshi,
Taniguchi Masaaki,
Hanai Takumi,
Mizuno Akira,
Shinagawa Nagao,
Kato Fumihiko
Publication year - 1988
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/014860718801200193
Subject(s) - catheter , body weight , medicine , anesthesia , surgery
A new apparatus incorporating a unique type of swivel device was devised for chronic intravenous infusion in unrestrained rats. The swivel requires very little torque for rotation, ie, one‐fourth that of the standard swivel, yet is 1/30 as expensive. A coil spring tube, located between the swivel and the catheter, allows the rat unhampered movement within the metabolic cage. Because the catheter follows the rats' movements freely, only two silk sutures are required to secure it to the animal. No statistically significant differences between experimental and control rats were observed in terms of body weight gain, food intake, nitrogen balance, or caloric efficiency. This apparatus should prove useful in many areas of research. ( Journal of Parenteral and Enteral Nutrition 12: 93–99, 1988)