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Successful Treatment of Superior Vena Cava Syndrome with Urokinase in an Infant
Author(s) -
Wilson Claire M.,
Merritt Russell J.,
Thomas Daniel W.
Publication year - 1988
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/014860718801200181
Subject(s) - urokinase , medicine , parenteral nutrition , superior vena cava syndrome , catheter , thrombus , clearance , thrombolysis , surgery , superior vena cava , enteral administration , central venous catheter , anesthesia , urology , myocardial infarction
An 11‐month‐old infant with a central venous catheter for total parenteral nutrition for short gut syndrome developed head and neck swelling. A thrombus at the catheter tip occluding the superior vena cava was demonstrated roentgenographically. A 48‐hr infusion of urokinase (4400 units/kg/ hr) was administered for thrombolysis. The thrombus cleared clinically and roentgenographically without adverse effects. There has been no recurrence of the superior vena cava syndrome. Urokinase infusion is an alternative to immediate catheter removal in selected patients. ( Journal of Parenteral and Enteral Nutrition 12: 81–83, 1988)