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A Comparison of Two 20% Lipid Emulsions
Author(s) -
Dahlstrom Karl Anders,
Mcintosh Norma,
Ament Marvin Earl
Publication year - 1987
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607187011002149
Subject(s) - calorie , parenteral nutrition , fat emulsion , medicine , crossover study , nitrogen balance , lipid emulsion , adverse effect , emulsion , gastroenterology , chemistry , biochemistry , nitrogen , alternative medicine , organic chemistry , pathology , placebo
Two different soy oil emulsions (Intralipid and Soyacal) were studied over a 2‐week period in a random crossover study to determine if there were clinical or biochemical differences between the two preparations when used in patients requiring total parenteral nutrition (TPN). Each fat emulsion was infused randomly over 1 week and then switched to the other. Eighteen adult patients requiring a minimum of 14 days TPN were studied. None of the 26 metabolic parameters evaluated was statistically different between the two groups. Analysis of nutritional status, irrespective of lipid infused, showed that the patients who received 56 kcal/kg/day with 37% of the nonprotein calories from lipids (1.8 ± 0.7 g/kcal/day) were in positive nitrogen balance on 80 of the 101 days studied. No adverse effects could be observed from either lipid emulsion during the short period of TPN used in this study. Both lipid emulsions were efficacious as a caloric source, and no clinical complications or biochemical abnormalities were found from either preparation. ( Journal of Parenteral and Enteral Nutrition 11:149–151, 1987)