Premium
Method For Evaluating Utilization of Infused Oligosaccharides in Postsurgical Patients
Author(s) -
Stegink Lewis D.,
Andersen Dean W.,
Zike Wilbur L.
Publication year - 1987
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607187011002124
Subject(s) - parenteral nutrition , oligosaccharide , hydrolysis , enteral administration , medicine , amylase , carbohydrate , urine , chemistry , intensive care medicine , biochemistry , enzyme
Oligosaccharides are potential sources of carbohydrate‐derived energy for use in parenteral nutrition regimens. Clinical studies indicate that although some patients utilize infused oligosaccharides well, many patients do not. These results suggest that oligosaccharides might be useful as a parenteral energy source for selected patients. This report describes a method, suitable for use by nursing staff on the ward, to determine oligosaccharide utilization and identify patients utilizing oligosaccharides well. Oligosaccharides excreted in urine are hydrolyzed enzymaticallly to glucose using α‐glucosidase and α‐amylase, and the glucose released is measured by a test tape method. The results obtained agree well with the acid hydrolysis‐spectrophotometric assay for oligosaccharide excretion used in earlier studies. The method readily identified postsurgical patients utilizing infused oligosaccharides poorly in both prospective and retrospective studies. ( Journal of Parenteral and Enteral Nutrition 11:124–128, 1987)