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Plasma Phospholipid Fatty Acids and Urinary Excretion of Prostaglandins PGE 1 and PGE2 in Infants during Total Parenteral Nutrition, with Continuous or Sequential Administration of Fat Emulsion
Author(s) -
Ghisolfi J.,
Garcia J.,
Thouvenot J.P.,
Olives J.P.,
Couvaras O.,
Boyer M.J.
Publication year - 1986
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607186010006631
Subject(s) - parenteral nutrition , phospholipid , excretion , urinary system , medicine , chemistry , fat emulsion , endocrinology , biochemistry , membrane
During total parenteral nutrition, using an identical supply of fat emulsion (350 mg/kg/24 hr) to correct essential fatty acid deficiency in children, the efficacy of two methods of administration was studied: continuous over 24 hr, or discontinuous 3 hr/day. At the beginning of the study, all the infants (1–4 months old) had proven essential fatty acid deficiency. After at least 1 month of one of the two nutritional protocols (continuous or discontinuous), plasma phospholipid fatty acid composition and PGE 1 and PGE 2 urinary excretion were measured. The results obtained indicate better utilization of the fat emulsion when it is administered almost every day, in continuous infusion over 24 hr (1 g/kg/24 hr of Intralipid 20%). ( Journal of Parenteral and Enteral Nutrition 10: 631–634, 1986)