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Fibronectin Levels in Stressed and Septic Patients Fed with Total Parenteral Nutrition
Author(s) -
Linden C.J.V.D.,
Buurman W.A.,
Spronken E.E.M.,
Soeters P.B.
Publication year - 1986
Publication title -
journal of parenteral and enteral nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 98
eISSN - 1941-2444
pISSN - 0148-6071
DOI - 10.1177/0148607186010004360
Subject(s) - parenteral nutrition , medicine , amino acid , enteral administration , fibronectin , chemistry , gastroenterology , biochemistry , extracellular matrix
Plasma fibronectin concentrations were measured in healthy persons as well as in septic and stressed patients. A decrease in plasma fibronectin concentration was shown in volunteers receiving a low energy (600 kcal), amino acids‐ and lipid‐deficient diet. Increased fibronectin levels were measured in stressed and septic patients, not receiving enteral nutrition, after adequate total parenteral nutrition (TPN during 1 week). It is concluded that total parenteral nutrition facilitates improved fibronectin synthesis in stressed and septic patients. Total parenteral nutrition containing an amino acid mixture rich in branched amino acids (50.2% BCAA) is not superior to TPN containing a standard amino acid mixture (15.6% BCAA) in this respect. (Journal of Parenteral and Enteral Nutrition 10:360–363, 1986)